TreVeyon Henderson averaged 10 yards per carry for the second time this season and led all running backs with 148 rushing yards in Week 15.
Five running backs reached 100 rushing yards in Week 15.
Only one of the five had 20 carries, which is a bit of an outlier from previous weeks.
Volume remains a critical component chasing rushing leaders, and volume is often correlated with a favorable game script.
Up to this point, 16 of the top 17 highest rushing totals on the season are from running backs on the winning team.
The one that was on the losing side lost by a single point in the final minute of the game.
In chasing most rushing yards or rushing yards over prop bets, identifying favorites or short dogs is a key component.
There are four games with double-digit favorites this week, which should be the starting point when searching for running backs who could be propelled to early leads and favorable volume for a spike week.
NFL Weekly Rushing Leaders, 2025:
| Week | Running Back | Rushing Yards | Opponent |
|---|---|---|---|
| 1 | Derrick Henry | 169 | Buffalo Bills |
| 2 | Jonathan Taylor | 165 | Denver Broncos |
| 3 | David Montgomery | 151 | Baltimore Ravens |
| 4 | Ashton Jeanty | 138 | Chicago Bears |
| 5 | Rico Dowdle | 206 | Miami Dolphins |
| 6 | Rico Dowdle | 183 | Dallas Cowboys |
| 7 | Jahmyr Gibbs | 136 | Tampa Bay Buccaneers |
| 8 | James Cook | 216 | Carolina Panthers |
| 9 | Kyle Monangai | 176 | Cincinnati Bengals |
| 10 | Jonathan Taylor | 244 | Atlanta Falcons |
| 11 | De'Von Achane | 120 | Washington Commanders |
| 12 | Jahmyr Gibbs | 219 | New York Giants |
| 13 | James Cook | 144 | Pittsburgh Steelers |
| 14 | Tony Pollard | 161 | Cleveland Browns |
| 15 | TreVeyon Henderson | 148 | Buffalo Bills |
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Most Week 16 Rushing Yards Prediction (Sunday): Bijan Robinson (+600)
Jawhar Jordan rushed for 100 yards against the Arizona Cardinals after coming off the bench last week.
The Falcons run the highest rate of outside zone runs, and the Cardinals rank 26th in EPA per rush against outside zone runs.
Robinson has averaged 19.8 carries over the past five weeks, and this matchup provides a solid marriage of volume and efficiency.
The Cardinals are a great team for overs and fantasy football since their games are averaging 127 plays as a result of the Cardinals' high pass volume.
Robinson had a season high 93.1% of the backfield touches last week.
He has had an extra few days of rest and is the current league leader in combined rushing and receiving yards.
With Tyler Allgeier hitting free agency in the offseason, there is a possible narrative around the Falcons chasing yards for the running back of the future.
The total in this matchup has ticked up, and this game provides Robinson an opportunity to combine volume and efficiency and a spike week in rushing yardage.
Week 16 Running Back Longshot Bet: Aaron Jones & Jordan Mason Combined Rushing Yards
- 100+ Rushing Yards (-126)
- 125+ Rushing Yards (+214)
- 150 Rushing Yards (+557)
The Minnesota Vikings are 3-point favorites against the New York Giants, who are dreadful at stopping the run this season.
After a solid performance against the Cowboys, J.J. McCarthy is garnering attention this week, when the answer is likely the Vikings' rushing attack.
The Giants are allowing the second-most yards to opposing running backs this season, averaging 123 yards against, and have lost 8 straight games.
Before facing the Cowboys, the Vikings defense averaged 137 passing yards against in their previous five games.
The likelihood of the Vikings jumping ahead and running the ball successfully is high, as the Giants could struggle to move the ball with a rookie quarterback against Brian Flores.
The combined rushing with Jones and Mason covers all the bases in terms of guessing which running back gets the carries and has the explosives.
The highest ladder of this combination has value if you believe the Vikings are going to lead this game.