NFL Week 7 is another good one. Up first on Thursday night is Pittsburgh taking on Cincinnati in an AFC North battle between the two oldest quarterbacks in the NFL (Aaron Rodgers and Joe Flacco). We'll see if the NFL Week 7 lines give more love to underdogs in primetime games (6-1 straight up against favorites in night games since Week 5).

NFL Week 7 Lines At a Glance

Game
Spread
Total

Steelers at Bengals(TNF)
PIT -5.5
43.5
Rams at Jaguars(London)
LAR -3
45
Raiders at Chiefs
KC -12
45.5
Saints at Bears
CHI -5.5
47.5
Dolphins at Browns
CLE -3
40.5
Patriots at Titans
NE -7
42
Eagles at Vikings
PHI -2
43.5
Panthers at Jets
CAR -1.5
42.5
Giants at Broncos
DEN -7
40
Colts at Chargers
LAC -1.5
48.5
Commanders at Cowboys
WAS -2
55
Packers at Cardinals
GB -6.5
44.5
Falcons at 49ers
SF -2
47.5
Buccaneers at Lions(MNF)
DET -5.5
53
Texans at Seahawks(MNF)
SEA -3.5
41

NFL Betting Lines Week 7: Odds, Storylines & Betting Tips

Sunday morning is another early start, with the Jacksonville Jaguars returning to their second home in London to take on the Los Angeles Rams, who may or may not have Puka Nacua available. The Sunday afternoon slate sees the Kansas City Chiefs playing a 1 p.m. game for the first time this season as they host the Las Vegas Raiders. Rashee Rice will make his season debut at wide receiver for the Silver and Black.

The late-afternoon window is highlighted by the Indianapolis Colts (5-1) traveling to SoFi Stadium to take on the Los Angeles Chargers after losing to the Rams there earlier this season. We'll also see the Cowboys and Commanders renew their NFC East rivalry. Jayden Daniels has led the Commanders to at least 18 points in his first 24 starts, the longest streak to begin a career in NFL history.

The NFL Week 7 odds see the Atlanta Falcons as a slight underdog on Sunday Night Football against the San Francisco 49ers, with Atlanta coming off a huge win over Buffalo last week. On Monday night, the first game in the doubleheader is arguably the marquee game of the week between the Buccaneers (5-1) and Lions (4-2) in Detroit. Finally, to end the week, it's the Houston Texans vs. the Seattle Seahawks, with Sam Darnold looking to continue his successful year.

Let's preview the full NFL Week 7 lines with the latest odds and a betting tip for each game. New sportsbook users can also get over $8,000 in NFL betting promos for this week's games.

Thursday | 8:15 PM ET | Pittsburgh Steelers vs. Cincinnati Bengals

  • Spread: PIT -5.5
  • Total: 43.5
  • Moneyline: Steelers (-275); Bengals (+225)
🎯 Betting Tip: Mike Tomlin's Steelers are 15-4 SU in Cincinnati since 2007, but he is 0-6 against the AFC North on Thursday night road games.

Sunday | 9:30 AM ET | Los Angeles Rams vs. Jacksonville Jaguars

  • Spread: LAR -3
  • Total: 45
  • Moneyline: Rams (-150); Jaguars (+125)
🎯 Betting Tip: The Rams and Jaguars are tied with six other teams for the best spread record in 2025 (4-2).

Sunday | 1:00 PM ET | Las Vegas Raiders vs. Kansas City Chiefs

  • Spread: KC -12
  • Total: 45.5
  • Moneyline: Raiders (+525); Chiefs (-750)
🎯 Betting Tip: In the Patrick Mahomes era, the Chiefs are 28-3 SU as a favorite of 10+ points; two of the losses were at home to the Raiders in 2020 (-11) and 2023 (-10.5).

Sunday | 1:00 PM ET | New Orleans Saints vs. Chicago Bears

  • Spread: CHI -5.5
  • Total: 47.5
  • Moneyline: Saints (+200); Bears (-250)
🎯 Betting Tip: The Saints are only 2-4 ATS but have been within one score in the fourth quarter in 5-of-6 games for rookie coach Kellen Moore.

Sunday | 1:00 PM ET | Miami Dolphins vs. Cleveland Browns

  • Spread: CLE -3
  • Total: 40.5
  • Moneyline: Dolphins (+135); Browns (-160)
🎯 Betting Tip: Since 2023, Kevin Stefanski's Browns are 6-2 ATS as a home favorite, the best record in that time.

Sunday | 1:00 PM ET | New England Patriots vs. Tennessee Titans

  • Spread: NE -7
  • Total: 42
  • Moneyline: Patriots (-325); Titans (+260)
🎯 Betting Tip: Mike Vrabel's Patriots are 4-2 ATS and have beaten the spread by an average of +5 points, the fifth-highest mark in 2025. Now he faces the team that fired him in 2022, the week they fired Brian Callahan, who was 0-10 ATS in home games.

Sunday | 1:00 PM ET | Philadelphia Eagles vs. Minnesota Vikings

  • Spread: PHI -2
  • Total: 43.5
  • Moneyline: Eagles (-130); Vikings (+110)
🎯 Betting Tip: Since 2021, Nick Sirianni's Eagles are 7-14 ATS after a loss (33.3%), the worst record in the league in that time.

Sunday | 1:00 PM ET | Carolina Panthers vs. New York Jets

  • Spread: CAR -1.5
  • Total: 42.5
  • Moneyline: Panthers (-125); Jets (+105)
🎯 Betting Tip: Jets quarterback Justin Fields is 0-26 when his opponent scores more than 20 points, which the Panthers have done in 4-of-6 games this season.

Sunday | 4:05 PM ET | New York Giants vs. Denver Broncos

  • Spread: DEN -7
  • Total: 40
  • Moneyline: Giants (+260); Broncos (-325)
🎯 Betting Tip: Since 2023, Denver coach Sean Payton is 10-6 ATS as a home favorite (62.5%).

Sunday | 4:05 PM ET | Indianapolis Colts vs. Los Angeles Chargers

  • Spread: LAC -1.5
  • Total: 48.5
  • Moneyline: Colts (+105); Chargers (-125)
🎯 Betting Tip: The Colts have outperformed the spread by 9.9 points, the highest average in 2025. The Chargers have underperformed the spread by -2.3 points (ranked 23rd).

Sunday | 4:25 PM ET | Washington Commanders vs. Dallas Cowboys

  • Spread: WAS -2
  • Total: 55
  • Moneyline: Commanders (-130); Cowboys (+110)
🎯 Betting Tip: This would only be the third NFL game since 2022 to have a total of at least 55 points. In division games with a total of at least 52 points since 2021, the over is just 6-11.

Sunday | 4:25 PM ET | Green Bay Packers vs. Arizona Cardinals

  • Spread: GB -6.5
  • Total: 44.5
  • Moneyline: Packers (-325); Cardinals (+260)
🎯 Betting Tip: Since 2019, Matt LaFleur's Packers are 16-14-1 ATS and 25-5-1 SU as a favorite of 6 or more points (3-6 ATS on the road).

Sunday | 8:20 PM ET | Atlanta Falcons vs. San Francisco 49ers

  • Spread: SF -2
  • Total: 47.5
  • Moneyline: Falcons (+110); 49ers (-130)
🎯 Betting Tip: 49ers coach Kyle Shanahan is 4-9 ATS and 6-7 SU as a favorite of 1 to 2.5 points since 2017.

Monday | 7:00 PM ET | Tampa Bay Buccaneers vs. Detroit Lions

  • Spread: DET -5.5
  • Total: 53
  • Moneyline: Buccaneers (+200); Lions (-250)
🎯 Betting Tip: Since 2021, Dan Campbell's Lions are 53-25 ATS (68%), the only team covering above 59.0% of spreads. Campbell is 20-9 ATS (69.0%) after a loss, which is also the best record in that time.

Monday | 10:00 PM ET | Houston Texans vs. Seattle Seahawks

  • Spread: SEA -3.5
  • Total: 41
  • Moneyline: Texans (+150); Seahawks (-185)
🎯 Betting Tip: Under coach Mike Macdonald (2024-25), the Seahawks are just 3-9 ATS at home, the second-worst record in the NFL.
BetMGM Odds for NFL Week 7 Lines

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