Another week, another round of significant injuries across the NFL.

As teams begin to game plan for Week 18, several will be doing so without key contributors.

From high-ankle sprains to potential season enders, here is a comprehensive look at the most impactful injuries from the past week of action and the initial timelines for their return.

Be sure to bookmark our NFL Injured Reserve Tracker, which will be updated weekly throughout the season.

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Biggest NFL Week 17 Injuries:

Luther Burden Injury Update

Bears rookie WR Luther Burden had 8 catches for 138 yards on Sunday night, but was seen limping into the x-ray room after injuring his hamstring on the final play of the game.

The Bears have already locked up the NFC North, but need a win over the Lions (or an Eagles loss) to clinch the second seed in the NFC playoffs.

Burdon was inactive last week due to an ankle injury, but this new one seems unrelated after his break-out performance against the 49ers.

Geno Smith Injury Update

Raiders QB Geno Smith exited Sunday's loss to the Giants with a high ankle sprain.

The always-optimistic Pete Carroll even told reporters he doesn't think Smith will be ready in time for next week's season finale so it will probably be Kenny Pickett under center as the Raiders try to secure the number one pick in the draft.

Pickett started for the Raiders in Week 15's shutout loss to the Eagles.

Amon-Ra St. Brown Injury Update

Lions WR Amon-Ra St. Brown went down with an apparent knee injury late in the Lions' loss to the Vikings on Christmas Day.

St. Brown came down awkwardly attempting to make a catch, with his leg seemingly getting caught underneath him as he fell to the ground.

He was questionable for the game due to a knee injury, but it is unclear whether he aggravated that injury or if this is a new issue.

With the Lions eliminated from the playoffs, it would not be a surprise if St. Brown's season is over even if the knee injury ends up being minor.

Malik Willis Injury Update

Packers QB Malik Willis aggravated his shoulder injury against the Ravens on Saturday night.

Willis appeared ready to return to the game after a short time in the locker room, but the Ravens put the game out of reach before he could get back on the field.

That suggests Willis will be ready to play in Week 18 if Jordan Love remains in the concussion protocol or if the Packers decide to sit their starters — they are locked into the No. 7 seed.

Javonte Williams Injury Update

Cowboys RB Javonte Williams suffered a shoulder injury against the Commanders on Christmas Day.

Williams rushed 13 times for 54 yards and a touchdown before leaving the game.

Malik Davis worked as the lead back with Williams sidelined, going over 100 yards on his 20 attempts.

With the Cowboys out of playoff contention, they could choose to shut down Williams even if his shoulder injury is not serious.

Breece Hall Injury Update

Jets RB Breece Hall did not finish the loss to the Patriots because of a knee injury.

After the game, Hall said his knee is fine, suggesting he plans to play in Week 18.

Hall rushed for 111 yards against New England including a 59-yard touchdown.

Jake Ferguson Injury Update

Cowboys TE Jake Ferguson did not play in the second half on Thursday because of a calf injury.

Ferguson only caught 1 pass before leaving, but it was a six-yard touchdown.

Both Brevyn Spann-Ford and Luke Schoonmaker saw targets with Ferguson sidelined.

Harold Fannin Injury Update

Browns TE Harold Fannin left Week 17 against the Steelers with a groin injury.

He originally suffered the injury in practice on Friday.

With a meaningless Week 18 game left on the schedule, the Browns could decide to shut down their talented young tight end.

Fannin caught 2 passes for 30 yards and a touchdown before leaving.

Other Notable Week 17 Injuries

  • Heading into a matchup that will decide the division, the Bucs have two big injuries to watch on defense. EDGE Haason Reddick exited Week 17 with a concussion, and CB Jamel Dean left because of a shoulder injury.
  • Commanders C Tyler Biadasz suffered knee and ankle injuries against the Cowboys on Thursday.
  • The Lions lost even more defenders on Thursday, with LB Alex Anzalone and S Thomas Harper leaving with concussions.
  • Steelers TE Darnell Washington suffered a broken arm, which will likely end his season.
  • Colts CB Sauce Gardner appeared to aggravate his calf injury and did not return against the Jaguars. With the Colts out of playoff contention, he will likely be shut down for the season.
  • Cardinals WR Marvin Harrison Jr. was questionable heading into Sunday due to a heel injury, but after starting the game, he exited early after aggravating it.
  • Seahawks WR Rashid Shaheed left Sunday's game due to a concussion. With Seattle ending their season on Saturday night, it would be a surprise if he cleared protocol in time to be active.