Bye weeks are done and dusted as we head into the final quarter stretch of the season. We've compiled the NFL Week 15 lines for this week's most important games, including the Ravens vs. Bengals, Bills vs. Patriots, and Chargers vs. Chiefs.

Here are the NFL Week 15 lines, along with the spreads, totals, key storylines, and a betting tip for each game on the schedule.

NFL Lines Week 15 At a Glance

Game
Spread
Total

Falcons at Buccaneers(TNF)
TB -4.5
44.5
Jets at Jaguars
JAX -12.5
41.5
Cardinals at Texans
HOU -9.5
42.5
Bills at Patriots
BUF -1.5
49.5
Chargers at Chiefs
KC -4.5
42.5
Raiders at Eagles
PHI -11.5
38.5
Ravens at Bengals
BAL -2.5
51.5
Commanders at Giants
NYG -2.5
46.5
Browns at Bears
CHI -7.5
39.5
Titans at 49ers
SF -12.5
44.5
Lions at Rams
LAR -5.5
54.5
Panthers at Saints
CAR -2.5
40.5
Packers at Broncos
GB -2.5
42.5
Colts at Seahawks
SEA -13.5
42.5
Vikings at Cowboys(SNF)
DAL -6.5
47.5
Dolphins at Steelers(MNF)
PIT -3.5
42.5

NFL Betting Lines Week 15: Spreads, Storylines & Things to Know

The NFL's Week 15 schedule is well-built, featuring plenty of interesting games that will impact the playoff races in both conferences. We could finally see some playoff spots and division titles clinched this Sunday.

It starts Thursday night with the Tampa Bay Buccaneers trying to get back on track after going 1-4 since the bye week, which has dropped them to 7-6. The Falcons haven't had a good year, but they can spoil Tampa's night with another upset after the Saints knocked off Tampa in this building on Sunday.

However, Sunday afternoon features all the best games in Week 15, rather than the island games. It gets underway with a huge 1:00 PM window on Sunday afternoon, featuring the marquee game in New England, something we haven't seen in several years. However, the Patriots, winners of 10 straight, can clinch the AFC East with a sweep of Buffalo, the team that has owned the division since Tom Brady left in 2020. The Bills were in a similar position in 2021 and came back to beat the Patriots and crush them in the playoffs. Still, it feels a little different this year with Drake Maye doing well and the Patriots already winning in Buffalo, an inconsistent team this year. But that's a huge game for Buffalo's last stand as AFC East champs.

Elsewhere in the early Sunday window, we'll get a Thanksgiving rematch between the Bengals and Ravens in Cincinnati after they already won in Baltimore with five takeaways. The Ravens are 6-7 and really slipping, too. The Bengals rarely ever beat Lamar Jackson, but Joe Burrow has handed him his two largest margins of defeat in his NFL career, including the 32-14 game on Thanksgiving.

We'll also see if the Eagles (8-5) and Chiefs (6-7) can halt their recent slides after reaching the Super Bowl last year. Both are struggling in a variety of ways, with Jalen Hurts and Patrick Mahomes combining for eight turnovers in Week 14. You'll know the Eagles, losers of three straight, are really going to collapse if they can't beat the lowly Raiders at home as a huge favorite. But we'll also see the Chiefs at Arrowhead taking on the Chargers, who saw Justin Herbert take a career-high 7.0 sacks on Monday night, one week after hand surgery. The Chargers will try to sweep the Chiefs, who are already guaranteed not to win the AFC West for the first time since 2015, and they could be eliminated from the playoffs entirely this week.

In the late-afternoon window, we could see a very bizarre game should the Colts actually start 44-year-old quarterback Philip Rivers, who came out of retirement after five years on Tuesday to sign with the practice squad following injuries to Daniel Jones and Riley Leonard. The Colts are truly desperate, but are they desperate enough to start a 44-year-old grandfather against one of the best defenses in football in Seattle? That could be some spectacle.

Otherwise, we're looking forward to Lions vs. Rams, and Matthew Stafford's former team has beaten him a few times in the last few years. However, the Lions need to prove they can win these types of games on the road as well. We'll also see the Packers as a road favorite against Denver in a non-conference matchup, so that's very interesting that the two AFC teams on 10-game winning streaks (Patriots and Broncos) are both home underdogs this week. But Green Bay is playing very well, too, behind Jordan Love and Micah Parsons.

On Sunday Night Football, you can't flex Jerry Jones and the Cowboys out of the national spotlight, no matter how much we'd like to try. The Cowboys will play the Vikings, who are coming off a 31-0 shutout of the Commanders. We'll see if J.J. McCarthy can have success against that Dallas defense, and the Cowboys (6-6-1) still have a slight shot in the NFC East.

Finally, on Monday Night Football, we'll see if the Steelers can keep up their winning ways at home on their only Monday night game this year, or if the Dolphins can brave the cold and prove this 4-game winning streak is legitimate and worthy of keeping coach Mike McDaniels around for 2026. Miami QB Tua Tagovailoa is 0-5 when it's 40 degrees or colder at kickoff.

That said, let's go through the NFL Week 15 lines with the latest odds and a betting tip for each game.

Thursday | 8:15 PM ET | Atlanta Falcons vs. Tampa Bay Buccaneers

  • Spread: TB -4.5
  • Total: 44.5
  • Moneyline: Falcons (+194); Buccaneers (-235)
🎯 Betting Fact: In 2024, Kirk Cousins threw 8 touchdowns in two games against Tampa Bay and 10 touchdowns in his other 12 games.

Sunday| 1:00 PM ET | New York Jets vs. Jacksonville Jaguars

  • Spread: JAX -12.5
  • Total: 41.5
  • Moneyline: Jets (+610); Jaguars (-900)
🎯 Betting Fact: The Jets are 3-1-1 ATS as a road underdog this season.

Sunday| 1:00 PM ET | Arizona Cardinals vs. Houston Texans

  • Spread: HOU -9.5
  • Total: 42.5
  • Moneyline: Cardinals (+420); Texans (-560)
🎯 Betting Fact: Jacoby Brissett has passed for at least 250 yards and 2 touchdowns in 7-of-8 starts for Arizona this season.

Sunday| 1:00 PM ET | Buffalo Bills vs. New England Patriots

  • Spread: BUF -1.5
  • Total: 49.5
  • Moneyline: Bills (-118); Patriots (+100)
🎯 Betting Fact: Mike Vrabel-coached teams are 3-1 SU against Josh Allen since 2020.

Sunday| 1:00 PM ET | Los Angeles Chargers vs. Kansas City Chiefs

  • Spread: KC -4.5
  • Total: 42.5
  • Moneyline: Chargers (+188); Chiefs (-225)
🎯 Betting Fact: The Chiefs are 4-2-1 ATS at home this season and have not allowed more than 20 points in any home game.

Sunday| 1:00 PM ET | Las Vegas Raiders vs. Philadelphia Eagles

  • Spread: PHI -11.5
  • Total: 38.5
  • Moneyline: Raiders (+560); Eagles (-770)
🎯 Betting Fact: Since 2023, the Eagles are 4-9 ATS after a loss, the worst record in the NFL during that time.

Sunday | 1:00 PM ET | Baltimore Ravens vs. Cincinnati Bengals

  • Spread: BAL -2.5
  • Total: 51.5
  • Moneyline: Ravens (-146); Bengals (+124)
🎯 Betting Fact: The over is 8-5 in Cincinnati games this season, tied for the second-highest rate in the league.

Sunday | 1:00 PM ET | Washington Commanders vs. New York Giants

  • Spread: NYG -2.5
  • Total: 46.5
  • Moneyline: Commanders (+116); Giants (-136)
🎯 Betting Fact: Washington is 4-9 ATS, tied with Baltimore for the worst spread record in 2025.

Sunday | 1:00 PM ET | Cleveland Browns vs. Chicago Bears

  • Spread: CHI -7.5
  • Total: 39.5
  • Moneyline: Browns (+330); Bears (-420)
🎯 Betting Fact: The Bears are 3-1 ATS as a favorite this season under rookie coach Ben Johnson.

Sunday | 4:25 PM ET | Tennessee Titans vs. San Francisco 49ers

  • Spread: SF -12.5
  • Total: 44.5
  • Moneyline: Titans (+640); 49ers (-950)
🎯 Betting Fact: The Titans scored a season-high 31 points in Week 14's win over Cleveland.

Sunday | 4:25 PM ET | Detroit Lions vs. Los Angeles Rams

  • Spread: LAR -5.5
  • Total: 54.5
  • Moneyline: Lions (+215); Rams(-260)
🎯 Betting Fact: Detroit coach Dan Campbell is 24-13 ATS as an underdog since 2021, the fourth-best record in the NFL in that time.

Sunday | 4:25 PM ET | Carolina Panthers vs. New Orleans Saints

  • Spread: CAR -2.5
  • Total: 40.5
  • Moneyline: Panthers (-158); Saints (+134)
🎯 Betting Fact: Under Dave Canales, Carolina is 5-4 ATS in NFC South games since 2024.

Sunday | 4:25 PM ET | Green Bay Packers vs. Denver Broncos

  • Spread: GB -2.5
  • Total: 42.5
  • Moneyline: Packers (-134); Broncos (+114)
🎯 Betting Fact: Under Matt LaFleur, the Packers are 11-17 ATS (39.3%) since 2019, the seventh-worst record in that time.

Sunday | 4:25 PM ET | Indianapolis Colts vs. Seattle Seahawks

  • Spread: SEA -13.5
  • Total: 42.5
  • Moneyline: Colts (+730); Seahawks (-1150)
🎯 Betting Fact: Seattle is a league-best 10-3 ATS and beats the spread by an average of +8.8 points. The Bet365 Indiana bonus code gives $150 in bonus bets guaranteed.

Sunday | 8:20 PM ET | Minnesota Vikings vs. Dallas Cowboys

  • Spread: DAL -6.5
  • Total: 47.5
  • Moneyline: Vikings (+225); Cowboys (-280)
🎯 Betting Fact: The over is 9-4 in Dallas games, the highest over rate in 2025 games.

Monday | 8:15 PM ET | Miami Dolphins vs. Pittsburgh Steelers

  • Spread: PIT -3.5
  • Total: 42.5
  • Moneyline: Dolphins (+160); Steelers (-190)
🎯 Betting Fact: The Steelers have won 22 straight home games on Monday Night Football (last loss: 1991).
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