Every week during the NFL season, our experts will share their favorite same game parlay picks from this week's action.
Same Game Parlays have grown in popularity in recent seasons as recreational gamblers are drawn to parlay bets.
Parlays are especially exciting for casual gamblers looking to win more than double the original bet.
The sportsbook edge on parlays is greater than on single bets because the edge is compounded during each additional bet.
This edge can be reduced by selecting correlated outcomes, as the likelihood of both occurring together may be higher than what the sportsbook's odds suggest.
By identifying correlated outcomes, there's a potential to turn a fun and recreational bet into a +EV opportunity.
What is a same game parlay?
A same game parlay is a wager that combines multiple bet outcomes or “legs” from a single game. Combining these bets increases the risk and, therefore, the potential payout if every leg hits.
These wagers are very often correlated, meaning if one of the legs wins, it is more likely the other legs will win as well.
Week 1 NFL Parlay Picks
Lions vs. Bills Same Game Parlay Picks
- Buffalo Bills Moneyline
- Buffalo Bills Team Total over 29.5
- Jared Goff Over 36.5 Pass Attempts
Odds: +206
The Lions are playing a short-week road game, following a Sunday overtime battle in which the defense was on the field for a league-high 86 snaps.
Monday's injury report listed only four names for the Lions.
Unfortunately, three are opening-week starters from the offensive line.
In 2025, the Lions trailed by 7 or more points at halftime twice.
Goff attempted 39 and 37 passes in those games.
Jahmyr Gibbs is coming off a career-high 29 rush attempts on short rest with offensive line injury concerns.
A small but simple parlay based on the Bills offense succeeding against a fatigued Lions defense, and the Lions leaning on Goff in a trailing game state.
Lions vs. Bills Same Game Parlay Picks
- Over 53.5
- Jahmyr Gibbs under 90.5 Rushing Yards
- Jahmyr Gibbs Over 5+ Receptions
- Amon-Ra St. Brown Over 8+ Receptions
- D.J. Moore Anytime Touchdown
Odds: +2600
The last time these two teams met, they scored 90 points.
The Lions defense played the most snaps on Sunday.
However, the Bills defense was on the field for the second most snaps.
Since the beginning of 2025, Gibbs has been targeted 35.4% of his routes when the ball is thrown in under 2 seconds.
Given the health of the offensive line and Gibbs' Week 1 usage, do the Lions use the quick passing game as an extension of the run game?
In his career, St. Brown has 4 games in which he has earned 18 or more targets, all of which were Lions losses.
Moore had 30.8% of the Bills' targets and 45.9% of the air yards in his debut.
The Lions' secondary presents a great opportunity for Moore to run back his solid start as a member of the Bills.
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