Use our free tool to find college football odds for the top games every week of the 2026 season.

Spreads, totals, and moneylines for the top college football games, plus expert picks from Ryan McCrystal.

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Consensus college football betting odds for the top matchups of Week 10, across DraftKings, FanDuel, BetMGM, Fanatics and Caesars. Odds last updated Friday, November 6 at 7:59 PM Eastern.
MatchupKickoff (Eastern)Point Spread (home team)Total Points (over/under)Moneyline (away / home)
Nebraska Cornhuskers at Illinois Fighting IlliniFriday, November 6, 8:05 p.m. ET+4.552.5-200 / +165
No. 22 New Mexico Lobos at Nevada Wolf PackFriday, November 6, 9:00 p.m. ET+1038.5-425 / +320
TCU Horned Frogs at No. 24 Arizona WildcatsFriday, November 6, 10:15 p.m. ET-746.5+220 / -275
No. 7 BYU Cougars at No. 3 Utah UtesSaturday, November 7, 12:00 p.m. ET-4.549.5+155 / -190
No. 5 UCLA Bruins at Minnesota Golden GophersSaturday, November 7, 12:00 p.m. ET+438.5-195 / +160
No. 10 Texas Longhorns at No. 19 Missouri TigersSaturday, November 7, 12:00 p.m. ET+2.542.5-142 / +120
Texas A&M Aggies at No. 23 South Carolina GamecocksSaturday, November 7, 3:00 p.m. ET-752.5+210 / -260
No. 9 Alabama Crimson Tide at No. 15 LSU TigersSaturday, November 7, 3:30 p.m. ET-6.552.5+192 / -235
Oregon Ducks at No. 11 Ohio State BuckeyesSaturday, November 7, 3:30 p.m. ET-7.545+240 / -300
Merrimack Warriors at No. 14 Wake Forest Demon DeaconsSaturday, November 7, 3:30 p.m. ET-47.558.5— / —
Cincinnati Bearcats at No. 17 Houston CougarsSaturday, November 7, 3:30 p.m. ET-10.561.5+320 / -400
Penn State Nittany Lions at Washington HuskiesSaturday, November 7, 3:30 p.m. ET-2.544.5+110 / -130
No. 20 Boise State Broncos at Colorado State RamsSaturday, November 7, 6:00 p.m. ET+1768.5-900 / +650
No. 8 Kentucky Wildcats at No. 16 Tennessee VolunteersSaturday, November 7, 6:15 p.m. ET-5.549.5+175 / -215
No. 1 Miami Hurricanes at No. 4 Notre Dame Fighting IrishSaturday, November 7, 7:30 p.m. ET-754.5+225 / -275
No. 2 Georgia Bulldogs at No. 12 Ole Miss RebelsSaturday, November 7, 7:30 p.m. ET+3.556.5-175 / +145
No. 21 Iowa Hawkeyes at Northwestern WildcatsSaturday, November 7, 7:30 p.m. ET+2.543.5-135 / +110
Louisville Cardinals at Georgia Tech Yellow JacketsSaturday, November 7, 7:30 p.m. ET+14.562.5-675 / +475
Oklahoma Sooners at No. 25 Florida GatorsSaturday, November 7, 7:45 p.m. ET-644.5+180 / -230
West Virginia Mountaineers at No. 13 Texas Tech Red RaidersSaturday, November 7, 9:30 p.m. ET-16.565.5+525 / -750
Sharp Football Analysis · Betting Odds
College Football Odds Top Games This Week
Consensus and best number across five sportsbooks
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Consensus is the most common line across the five books shown, not a sportsbook's price. Lines move. Confirm the number at the sportsbook before you bet.

Ryan McCrystal's College Football Picks: Week 10 Best Bets

Finding the Best Number

Margins in sports betting are razor-thin, so finding the best number matters.

That is especially true in college football, where key numbers are a little less important than in the NFL.

Betting volume is also lower, which means the numbers aren't quite as sharp.

That is especially true when looking at smaller schools and conferences.

All of that leads to bigger differences between lines at the top sportsbooks in college football, which makes shopping for the best line even more important.

Use our College Football Odds tool at the top of this page to find the best game lines, totals, and moneylines for the top college football games every week.