Use our free tool to find NFL odds every week of the 2026 season.
Spreads, totals, and moneylines for every NFL game, plus expert picks from Josh Shepardson.
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Week 7 NFL Betting Odds
| Matchup | Kickoff (Eastern) | Point Spread (home team) | Total Points (over/under) | Moneyline (away / home) |
|---|---|---|---|---|
| Washington Commanders at San Francisco 49ers | Monday, October 19, 8:15 p.m. ET (week 6) | -7.5 | 51.5 | +320 / -425 |
| New England Patriots at Chicago Bears | Thursday, October 22, 8:15 p.m. ET | -3 | 50.5 | +135 / -160 |
| Pittsburgh Steelers at New Orleans Saints | Sunday, October 25, 9:30 a.m. ET | +3 | 44.5 | -175 / +145 |
| San Francisco 49ers at Atlanta Falcons | Sunday, October 25, 1:00 p.m. ET | +4.5 | 50.5 | -225 / +180 |
| Cincinnati Bengals at Baltimore Ravens | Sunday, October 25, 1:00 p.m. ET | -2.5 | 51 | +125 / -150 |
| Tampa Bay Buccaneers at Carolina Panthers | Sunday, October 25, 1:00 p.m. ET | -3 | 44.5 | +140 / -178 |
| Cleveland Browns at Tennessee Titans | Sunday, October 25, 1:00 p.m. ET | +2 | 38.5 | -125 / +105 |
| New York Giants at Houston Texans | Sunday, October 25, 1:00 p.m. ET | -9.5 | 43 | +375 / -500 |
| Indianapolis Colts at Minnesota Vikings | Sunday, October 25, 1:00 p.m. ET | -6 | 41.5 | +220 / -270 |
| Miami Dolphins at New York Jets | Sunday, October 25, 1:00 p.m. ET | -4.5 | 39.5 | +190 / -235 |
| Denver Broncos at Arizona Cardinals | Sunday, October 25, 4:05 p.m. ET | +4 | 43.5 | -225 / +190 |
| Green Bay Packers at Detroit Lions | Sunday, October 25, 4:25 p.m. ET | -3 | 52.5 | +140 / -166 |
| Los Angeles Rams at Las Vegas Raiders | Sunday, October 25, 4:25 p.m. ET | +4.5 | 47.5 | -210 / +180 |
| Kansas City Chiefs at Seattle Seahawks | Sunday, October 25, 8:20 p.m. ET | -2.5 | 42.5 | +115 / -135 |
| Dallas Cowboys at Philadelphia Eagles | Monday, October 26, 8:15 p.m. ET | +4.5 | 44.5 | -225 / +185 |
Josh Shepardson's NFL Picks: Week 7 Best Bets
Coming Soon!
Joe Gibbs' Referee Analysis & Week 7 Betting Impact
Coming Soon!
Finding the Best Number
Margins in sports betting are razor-thin, so finding the best number matters.
That is especially true in the NFL, where key numbers matter more than in any other sport.
Around 15% of NFL games end in a 3-point margin, which means the difference between -2.5 or -3.5 and -3 is massive.
Unsurprisingly, 7 is the second-most important key number, though the new extra-point rule has adjusted things a bit.
In addition to more missed extra points, teams are going for two more often after touchdowns.
From 2015 to 2025, teams went for two after 9% of touchdowns league-wide.
The ten years before that, the rate was 4.4%.
As a result, 6-point, 8-point, and even 5-point margins have become more prominent.
Use our NFL Odds tool at the top of this page to find the best game lines, totals, and moneylines for every NFL game this season.
NFL Point Spread Key Numbers
- 3 points
- 7 points
- 10 points
- 6 points
- 8 points
