Week 10 of the NFL DFS season has arrived, and it is time to win some big money using stacks.
While fantasy football stacks are becoming more prevalent in redraft leagues, the ability to stack players has always been one of the main strategic plays in daily fantasy.
This weekly article will focus on the best stack plays in a given week for DFS.
While these plays can apply to FanDuel and other daily fantasy sites, this article will focus primarily on DraftKings pricing.
What is stacking in DFS?
A fantasy football stack is when you take two or more players from the same team to double your chances of a big score if that team does well. This is a strategy that is especially useful in games with high over unders.
While you can stack a quarterback with a running back and or a tight end, we’ll be focusing on the best stacks available between a quarterback and his pass catchers.
What is most important when stacking in DFS?
What is most important to pay attention to, with or without stacking, is a player's cost and their ultimate output of points.
Ultimately, factoring in the elements of stacking players along with a strong return on investment on players' costs will put you in the best position to cash in this season.
Get an in-depth fantasy preview for every game with Rich Hribar's Week 10 Worksheets!
| Matchup | Time |
|---|---|
| Raiders @ Broncos | Thursday Night Football |
| Falcons @ Colts | Sunday -- 9:30 a.m. ET |
| Giants @ Bears | Sunday -- 1 p.m. ET |
| Bills @ Dolphins | Sunday -- 1 p.m. ET |
| Ravens @ Vikings | Sunday -- 1 p.m. ET |
| Browns @ Jets | Sunday -- 1 p.m. ET |
| Patriots @ Bucs | Sunday -- 1 p.m. ET |
| Saints @ Panthers | Sunday -- 1 p.m. ET |
| Jaguars @ Texans | Sunday -- 1 p.m. ET |
| Cardinals @ Seahawks | Sunday -- 4:05 p.m. ET |
| Rams @ 49ers | Sunday -- 4:25 p.m. ET |
| Lions @ Commanders | Sunday -- 4:25 p.m. ET |
| Steelers @ Chargers | Sunday Night Football |
| Eagles @ Packers | Monday Night Football |
Week 10 NFL DFS Stacks & Picks for DraftKings, FanDuel
Without further ado, here are some of the best DFS stack options for Week 10 of the 2025 NFL season:
QB Jacoby Brissett ($4,600) & TE Trey McBride ($6,000)
- Combined Price: $10,400 – 20.8% of lineup salary
Jacoby Brissett is not the flashiest name in daily fantasy, but he is worth paying attention to.
In Brissett’s three games as the Cardinals starter this season, he has thrown for 6 touchdowns and only 1 interception.
With those sorts of numbers, it should be no surprise that Brisset has averaged 23.4 points per game.
It is also a Cardinals team that, despite their starting quarterback being down, the offense has stuck with the passing game.
Over the last three weeks, the Cardinals have averaged 37 pass attempts, which is the fifth-most in the league, and 2.9 more than the offense had attempted all season.
Primarily, this article focuses on stacks with quarterbacks and wide receivers, but when discussing the Cardinals, Trey McBride makes too much sense.
The difference between Kyler Murray and Brissett being under center is noticeable.
When Murray was starting in Weeks 1 through 5, McBride had a 27% team target share and accounted for 17% of the team’s touchdowns.
With Brissett taking over in Weeks 6 through 9, those numbers went to a 32% team target share and 67% of the touchdowns.
It is also worth noting that while the Seahawks are allowing the seventh fewest points to wide receivers, they are 13th in most points allowed to tight ends.
